The Seaver Autism Center for Research and Treatment at Mount Sinai is interested in testing the hypothesis described in this site. Since my presentation in November 2007 there have been sufficient anecdotal reports of improvements in self-injurious and repetitive behaviors to warrant further study.
http://clinicaltrials.gov/ct2/show/NCT01040221
This will be a 16 week, open-label trial of TSO to assess the effect on repetitive behaviors, aggression and irritability, and global functioning in adults with autistic disorder. The objectives of the proposed study are to develop an innovative treatment approach to autism by 1) assessing the safety and efficacy of TSO treatment using behavioral and laboratory outcome measures; 2) determining whether this treatment has sufficient promise to warrant consideration of a larger, multi-centered, placebo-controlled clinical trial; 3) conducting secondary analyses to explore the relationship between clinical features, immune mechanisms, and treatment response.
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